Osmosis Jones

2001 Comedy

Peter Farrelly and Bobby Farrelly, the impish impresarios of gross-out comedy, take their body function-inspired humor to new extremes in this mixture of live action and animation. Bill Murray stars as Frank, a zoo worker suffering from the effects of an unknown malady he contracted after eating an egg contaminated with simian saliva. Unknown to Frank, the inside of his body is actually a city (the City of Frank) teeming with cellular life, where the mysterious illness he's fighting is an invading enemy that must be defeated at all costs. It's up to Osmosis Jones (voice of Chris Rock), a white blood cell cop, and Drix (voice of David Hyde Pierce), a rookie over-the-counter medication, to hunt down and stop a lethal virus (Laurence Fishburne) who's got an inferiority complex. Along the way, the partners visit Frank's runny nostrils (Booger Dam) and a bar called, appropriately enough, the Zit. Osmosis Jones costars Molly Shannon and Chris Elliott, and features the vocal talents of William Shatner, producer Joel Silver, and singer Brandy Norwood. more..

Director: Peter Farrelly

Starring: Bill Murray

Reviews

  • Gets under your skin with laughs that are fast, slick and slippery and with visuals as vivid as anything this side of Demerol.

    Robert K. Elder - The Chicago Tribune

    26 April 2013

  • Oscillates between streaky black comedy and sanitary instruction.

    Lisa Schwarzbaum - Entertainment Weekly

    26 April 2013

  • Warts and all, Osmosis Jones is the year's ultimate bodily functions comedy.

    - Los Angeles Times

    26 April 2013

  • A genuinely eccentric comedy that explodes with funny ideas and expresses most of them in wildly original animation.

    Joe Morgenstern - The Wall Street Journal

    26 April 2013

  • Likely to entertain kids, who seem to like jokes about anatomical plumbing. For adults, there is the exuberance of the animation and the energy of the whole movie, which is just plain clever.

    Roger Ebert - The Chicago Sun-Times

    26 April 2013

Awards

  • Outstanding Achievement in an Animated Theatrical Feature

    Annie Awards (2001)

     
  • Bobby Farrelly

    Montréal Comedy Festival 'Just for Laughs' (2001)

  • Best Sound Editing - Animated Feature Film, Domestic and Foreign

    Motion Picture Sound Editors (2002)